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Managing side effects from both Its helpful to know what to expect so you can distinguish between normal vaccine reactions and Wegovy side effects: Common flu jab reactions: Sore arm at injection site (very common) Mild tiredness or headache (1-2 days) Slight temperature or aching (less common) How these differ from Wegovy side effects: Flu jab reactions are typically short-lived (24-48 hours) Arm soreness is specific to the vaccine, not a Wegovy effect Any nausea is more likely from Wegovy than the vaccine Tips for comfort: Take paracetamol for arm soreness or mild fever Rest and stay hydrated Apply a cool compress to the injection site Continue your normal Wegovy routine Cold and flu tips while on Wegovy If you do catch a cold or flu despite vaccination, most over-the-counter medicines are safe with Wegovy 1 : Safe options: Paracetamol for fever and aches Throat lozenges and warm drinks Rest and plenty of fluids Simple cough mixtures Continue to eat a diet based on whole foods and minimise ultra-processed foods Use with caution: Decongestants (can affect blood pressure) Ibuprofen (may irritate stomach, especially with Wegovys digestive effects) Medicines containing sugar (check labels if managing diabetes) Always check with your pharmacist when buying cold and flu medicines

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However, you may experience typical side effects of each, such as gastrointestinal discomfort from semaglutide and possible hormonal side effects from contraceptives

Hiatt WR, Goldfine AB, Kaul S